Update on the development of molecular imaging and nanomedicine in China: Optical imaging

Lina Wu; Hongyan Zou; Hongbin Wang; Sihang Zhang; Shuang Liu; Ying Jiang; Jing Chen; Yingbo Li; Mengping Shao; Ruixin Zhang; Xiaona Li; Jing Dong; Lili Yang; Kai Wang; Xinyuan Zhu; Xilin Sun

doi:10.1002/wnan.1660

Update on the development of molecular imaging and nanomedicine in China: Optical imaging

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2021 Jan;13(1):e1660. doi: 10.1002/wnan.1660. Epub 2020 Jul 29.

Authors

Lina Wu^{1

2}, Hongyan Zou^{1

2}, Hongbin Wang^{1

2}, Sihang Zhang³, Shuang Liu^{1

2}, Ying Jiang^{1

2}, Jing Chen^{1

2}, Yingbo Li^{1

2}, Mengping Shao^{1

2}, Ruixin Zhang^{1

2}, Xiaona Li^{1

2}, Jing Dong^{1

2}, Lili Yang^{1

2}, Kai Wang^{1

2}, Xinyuan Zhu⁴, Xilin Sun^{1

2}

Affiliations

¹ NHC and CAMS Key Laboratory of Molecular Probe and Targeted Theranostics, Molecular Imaging Research Center (MIRC), Harbin Medical University, Harbin, China.
² TOF-PET/CT/MR Center, The Fourth Hospital of Harbin Medical University, Harbin, China.
³ Elsevier B.V., Amsterdam, Netherlands.
⁴ School of Chemistry and Chemical Engineering, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Shanghai Jiao Tong University, Shanghai, China.

PMID: 32725869
DOI: 10.1002/wnan.1660

Abstract

Molecular imaging has received increased attention worldwide, including in China, because it offers noninvasive characterization of widely diverse clinically significant pathologies. To achieve these goals, nanomedicine has evolved into a broad interdisciplinary field with flexible designs to accommodate and concentrate imaging and therapeutic payloads into pathological cells through selective binding to disease specific cell membrane biomarkers. This concept of personalized medicine reflects the vision of "magic bullets" proposed by German biochemist Paul Ehrlich over 100 years ago. As happening worldwide, Chinese scientists are contributing to this tsunami of science and technologies through impactful national programs and international research collaborations. This review provides a comprehensive update of Chinese innovations to address intractable unmet medical need in China and worldwide in the optical sciences. This article is categorized under: Diagnostic Tools > in vivo Nanodiagnostics and Imaging.

Keywords: China; molecular imaging; nanomedicine; optical imaging.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

China
Molecular Imaging*
Nanomedicine*
Optical Imaging*
Precision Medicine