Advances in Exosomes Derived from Different Cell Sources and Cardiovascular Diseases

Biomed Res Int. 2020 Jul 7:2020:7298687. doi: 10.1155/2020/7298687. eCollection 2020.

Abstract

Exosomes can reach distant tissues through blood circulation to communicate directly with target cells and rapidly regulate intracellular signals. Exosomes play an important role in cardiovascular pathophysiology. Different exosomes derived from different sources, and their cargos have different mechanisms of action. In addition to being biomarkers, exosomes also have a certain significance in the diagnosis, treatment, and even prevention of cardiovascular diseases. Here, we provide a review of the up-to-date applications of exosomes, derived from various sources, in the prognosis and diagnosis of cardiovascular diseases.

Publication types

  • Review

MeSH terms

  • Animals
  • Biomarkers / metabolism
  • Cardiovascular Diseases / diagnosis*
  • Cardiovascular Diseases / metabolism
  • Cardiovascular Diseases / pathology
  • Exosomes / pathology*
  • Humans

Substances

  • Biomarkers