Software and Methods for Computational Flux Balance Analysis

Methods Mol Biol. 2020:2096:165-177. doi: 10.1007/978-1-0716-0195-2_13.

Abstract

As genetic engineering of organisms has grown easier and more precise, computational modeling of metabolic systems has played an increasingly important role in both guiding experimental interventions and in understanding the results of metabolic perturbations.

Keywords: Computational Model; Constraint-based reconstruction and analysis; Flux Balance Analysis; Metabolic networks; Strain design.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Escherichia coli / drug effects
  • Escherichia coli / growth & development
  • Glucose / metabolism
  • Metabolic Flux Analysis / methods*
  • Metabolic Networks and Pathways / drug effects
  • Models, Biological
  • Oxygen / pharmacology
  • Phenotype
  • Software*
  • Sorbic Acid / analogs & derivatives
  • Sorbic Acid / metabolism

Substances

  • muconic acid
  • Glucose
  • Oxygen
  • Sorbic Acid