Stereotactic Body Radiation Therapy (SBRT) in Pelvic Lymph Node Oligometastases

Cancer Invest. 2020 Nov;38(10):599-607. doi: 10.1080/07357907.2020.1801713. Epub 2020 Oct 2.

Abstract

The role of stereotactic body radiation therapy (SBRT) in achieving durable local control and palliation of pain in pelvic lymph node oligometastatic disease is not well-studied. We performed a retrospective analysis of 30 patients with 43 pelvic lymph node oligometastases from various primary cancers all but one with non-prostate primaries treated at our institution with SBRT. The median follow-up time was 21 months. The median SBRT dose was 24 Gy in four fractions. The one-, two-, and five-year local control was 74%, 71%, and 70% and one-, two-, and five-year overall survival was 70%, 47%, and 31%. Toxicities were mild with no grade 3 or higher.

Keywords: Stereotactic body radiation therapy (SBRT); oligometastatic disease; palliative radiotherapy; pelvic metastases.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Female
  • Follow-Up Studies
  • Humans
  • Lymph Nodes / pathology
  • Lymph Nodes / surgery*
  • Male
  • Middle Aged
  • Neoplasms / pathology
  • Neoplasms / surgery*
  • Pelvic Neoplasms / secondary
  • Pelvic Neoplasms / surgery*
  • Prognosis
  • Radiosurgery / mortality*
  • Retrospective Studies
  • Survival Rate