Behavioral Functioning and Quality of Life in South African Children Living with HIV on Antiretroviral Therapy

Stephanie Shiau; Henry Evans; Renate Strehlau; Yanhan Shen; Megan Burke; Afaaf Liberty; Ashraf Coovadia; Elaine J Abrams; Michael T Yin; Avy Violari; Louise Kuhn; Stephen M Arpadi

doi:10.1016/j.jpeds.2020.07.057

Behavioral Functioning and Quality of Life in South African Children Living with HIV on Antiretroviral Therapy

J Pediatr. 2020 Dec:227:308-313.e2. doi: 10.1016/j.jpeds.2020.07.057. Epub 2020 Jul 23.

Authors

Affiliations

¹ Department of Biostatistics and Epidemiology, Rutgers School of Public Health, Piscataway, NJ.
² Department of Medicine, Division of Infectious Diseases, Vagelos College of Physicians & Surgeons, Columbia University Irving Medical Center, New York, NY.
³ Empilweni Services and Research Unit, Rahima Moosa Mother and Child Hospital, Department of Pediatrics and Child Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
⁴ ICAP at Columbia University, Mailman School of Public Health, Columbia University Irving Medical Center, New York, NY.
⁵ Department of Epidemiology, Mailman School of Public Health, Columbia University Irving Medical Center, New York, NY.
⁶ Department of Pediatrics, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY; G.H. Sergievsky Center, Vagelos College of Physicians & Surgeons, Columbia University Irving Medical Center, New York, NY; Perinatal HIV Research Unit, Chris Hani Baragwanath Hospital, University of the Witwatersrand, Johannesburg, South Africa.
⁷ ICAP at Columbia University, Mailman School of Public Health, Columbia University Irving Medical Center, New York, NY; G.H. Sergievsky Center, Vagelos College of Physicians & Surgeons, Columbia University Irving Medical Center, New York, NY.
⁸ ICAP at Columbia University, Mailman School of Public Health, Columbia University Irving Medical Center, New York, NY; G.H. Sergievsky Center, Vagelos College of Physicians & Surgeons, Columbia University Irving Medical Center, New York, NY; Perinatal HIV Research Unit, Chris Hani Baragwanath Hospital, University of the Witwatersrand, Johannesburg, South Africa. Electronic address: sma2@columbia.edu.

Abstract

This study examined behavioral functioning and quality of life in South African children living with perinatally acquired HIV. Compared with controls, children living with perinatally acquired HIV had a higher mean total difficulties score assessed by the Strengths and Difficulties Questionnaire and lower mean quality of life scores assessed by the Pediatric Quality of Life Inventory.

Publication types

Case Reports
Research Support, N.I.H., Extramural

MeSH terms

Adolescent
Anti-Retroviral Agents / therapeutic use*
Child
Cross-Sectional Studies
Female
HIV Infections / drug therapy*
HIV Infections / psychology*
Humans
Male
Problem Behavior*
Quality of Life*
South Africa

Substances

Anti-Retroviral Agents

Abstract

Publication types

MeSH terms

Substances

Grants and funding