Protection of natural antioxidants against low-density lipoprotein oxidation

Adv Food Nutr Res. 2020:93:251-291. doi: 10.1016/bs.afnr.2020.04.002. Epub 2020 May 4.

Abstract

This chapter reports essential information about the protective action of antioxidants against LDL oxidation. The activity of individual compounds (tocopherols, vitamin C, phenolic compounds) as well as extracts obtained from plant material (cereals, fruits, legumes, nuts, mushrooms, by-products of food industry) is reported. The structure-antioxidant activity relationship of phenolic compounds is discussed. This article summarizes the findings to date of both in vitro and in vivo studies using foods or phenolic extracts isolated from foodstuffs at inhibiting the incidence of LDL oxidation. This chapter summarizes also the reportings to date of in vivo studies using foods or beverages at inhibiting the incidence of LDL oxidation.

Keywords: Antioxidant activity; Atherosclerosis; In vitro studies; In vivo studies; LDL oxidation; Phenolics.

Publication types

  • Review

MeSH terms

  • Animals
  • Antioxidants / pharmacology*
  • Ascorbic Acid / pharmacology
  • Biological Products / pharmacology
  • Diet*
  • Female
  • Humans
  • Lipoproteins, LDL / metabolism*
  • Male
  • Oxidation-Reduction
  • Phenols / pharmacology*
  • Plant Extracts / pharmacology*
  • Plants, Edible / chemistry*
  • Tocopherols / pharmacology

Substances

  • Antioxidants
  • Biological Products
  • Lipoproteins, LDL
  • Phenols
  • Plant Extracts
  • oxidized low density lipoprotein
  • Ascorbic Acid
  • Tocopherols