Cardiac myxoma misdiagnosed as infective endocarditis: a case of Carney complex

J Cardiothorac Surg. 2020 Jul 25;15(1):188. doi: 10.1186/s13019-020-01238-4.

Abstract

Background: Infective endocarditis and cardiac myxoma have common features including fever, systemic embolism and intra-cardiac masses. For this reason, these diseases are often misdiagnosed one for another despite proper imaging studies. Herein, we report a case of suspected infective endocarditis in a patient with acute stroke, fever and a mass adjacent to the mitral valve.

Case presentation: A 24-year-old male patient presented with recurrent fever and stroke. In view of a history of Cushing syndrome and a mobile mass in the left atrium, infective endocarditis was highly suspected. He was transferred for emergency cardiac surgical intervention. During surgery, intraoperative transesophageal echocardiography revealed a 7 cm mass attached to the interatrial septum. The mass was excised through right mini-thoracotomy and pathological examination confirmed the presence of a myxoma. Based on the above clinical findings and genetic analysis, the diagnosis of Carney complex was confirmed.

Conclusions: Infective endocarditis and cardiac myxoma have common features and can be misdiagnosed. If a young patient presenting with embolic stroke had a history of an endocrine neoplasm, Carney complex should be considered in the differential diagnosis of infective endocarditis.

Keywords: Carney complex; Cerebral infarction; Cushing syndrome; Infective endocarditis; Myxoma.

Publication types

  • Case Reports

MeSH terms

  • Carney Complex / complications
  • Carney Complex / diagnosis*
  • Carney Complex / surgery*
  • Diagnostic Errors
  • Echocardiography, Transesophageal
  • Endocarditis / diagnostic imaging*
  • Fever / etiology
  • Humans
  • Male
  • Stroke / etiology
  • Young Adult