Surgery and Perioperative Management in Small Intestinal Neuroendocrine Tumors

J Clin Med. 2020 Jul 21;9(7):2319. doi: 10.3390/jcm9072319.

Abstract

Small-intestinal neuroendocrine tumors (SI-NETs) are the most prevalent small bowel neoplasms with an increasing frequency. In the multimodal management of SI-NETs, surgery plays a key role, either in curative intent, even if R0 resection is feasible in only 20% of patients due to advanced stage at diagnosis, or palliative intent. Surgeons must be informed about the specific surgical management of SI-NETs according to their hormonal secretion, their usual dissemination at the time of diagnosis and the need for bowel-preserving surgery to avoid short bowel syndrome. The aim of this paper is to review the surgical indications and techniques, and perioperative and postoperative management of SI-NETs.

Keywords: carcinoid crisis; carcinoid syndrome; small bowel neuroendocrine tumor; surgery.

Publication types

  • Review