One Hundred Faces of Geraniol

Molecules. 2020 Jul 21;25(14):3303. doi: 10.3390/molecules25143303.

Abstract

Geraniol is a monoterpenic alcohol with a pleasant rose-like aroma, known as an important ingredient in many essential oils, and is used commercially as a fragrance compound in cosmetic and household products. However, geraniol has a number of biological activities, such as antioxidant and anti-inflammatory properties. In addition, numerous in vitro and in vivo studies have shown the activity of geraniol against prostate, bowel, liver, kidney and skin cancer. It can induce apoptosis and increase the expression of proapoptotic proteins. The synergy of this with other drugs may further increase the range of chemotherapeutic agents. The antibacterial activity of this compound was also observed on respiratory pathogens, skin and food-derived strains. This review discusses some of the most important uses of geraniol.

Keywords: anticancer; antimicrobial; antioxidant; bioactivity; geraniol.

Publication types

  • Review

MeSH terms

  • Acyclic Monoterpenes / chemistry*
  • Acyclic Monoterpenes / metabolism
  • Acyclic Monoterpenes / pharmacology*
  • Animals
  • Anti-Infective Agents / chemistry
  • Anti-Infective Agents / pharmacology
  • Anti-Inflammatory Agents / chemistry
  • Anti-Inflammatory Agents / pharmacology
  • Antineoplastic Agents / chemistry
  • Antineoplastic Agents / pharmacology
  • Antioxidants / chemistry
  • Antioxidants / pharmacology
  • Humans
  • Odorants
  • Oils, Volatile / chemistry
  • Perfume / chemistry

Substances

  • Acyclic Monoterpenes
  • Anti-Infective Agents
  • Anti-Inflammatory Agents
  • Antineoplastic Agents
  • Antioxidants
  • Oils, Volatile
  • Perfume
  • geraniol