Carboxymethyl cellulose-based materials for infection control and wound healing: A review

Int J Biol Macromol. 2020 Dec 1:164:963-975. doi: 10.1016/j.ijbiomac.2020.07.160. Epub 2020 Jul 21.

Abstract

The development of ideal wound dressing materials with excellent characteristics is currently a major demand in wound therapy. In recent years, carboxymethyl cellulose (CMC)-based wound dressing materials have been of immense attraction due to their noble properties, such as: biocompatibility, biodegradability, tissue resembling, low cost and non-toxic. It is used extensively, in a variety of applications in the biomedical and pharmaceutical fields. The hydrophilic nature of CMC, makes it possible to blend and cross-link with other materials, such as: synthetic polymers, natural polymers and inorganic materials and it enables the preparation of innovative wound dressing biomaterials. Hence, this review, focuses on the intrinsic characteristics of CMC-based wound dressing materials, including hydrogels, films, 3D printing, fibres, gauzes and their recent advancements in chronic wound healing.

Keywords: Antimicrobial; Biomedical; Carboxymethyl cellulose; Wound dressing.

Publication types

  • Review

MeSH terms

  • Animals
  • Bandages*
  • Biocompatible Materials / chemistry*
  • Carboxymethylcellulose Sodium / chemistry*
  • Cellulose
  • Humans
  • Hydrogels / chemistry
  • Infection Control
  • Mice
  • Nanoparticles / chemistry*
  • Polymers / chemistry*
  • Printing, Three-Dimensional
  • Ulcer
  • Wound Healing*

Substances

  • Biocompatible Materials
  • Hydrogels
  • Polymers
  • Cellulose
  • Carboxymethylcellulose Sodium