Reversible bradycardia secondary to myxedema coma: case-report

Rev Cardiovasc Med. 2020 Jun 30;21(2):297-301. doi: 10.31083/j.rcm.2020.02.26.

Abstract

Myxedema coma occurs mostly in patients with long-standing untreated or undertreated hypothyroidism. Bradycardia is a well-known cardiac manifestation for myxedema coma; however, not all bradycardia with hypothyroidism are sinus bradycardia. Sick sinus syndrome is a group of arrhythmias caused by the malfunction of the natural pacemaker of the heart. Tachy-Brady syndrome is considered to be a type of sick sinus syndrome, where the heart alternates between tachycardia and bradycardia, and it is usually treated with pacemaker implantation along with rate slowing medical therapy. Here we report a case of an 83-year-old female who presented with myxedema coma and atrial fibrillation with tachycardia and intermittent slow ventricular response. We attempt to review the relationship between these two diseases and conclude that appropriate diagnosis of myxedema coma, may be beneficial in reducing the need for pacemaker implantation.

Keywords: Atrial fibrillation with slow ventricular rate; case report; hypothyroidism; myxedema.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged, 80 and over
  • Bradycardia / diagnosis
  • Bradycardia / etiology*
  • Bradycardia / physiopathology
  • Bradycardia / therapy
  • Cardiac Pacing, Artificial
  • Coma / diagnosis
  • Coma / drug therapy
  • Coma / etiology*
  • Coma / physiopathology
  • Female
  • Heart Rate* / drug effects
  • Hormone Replacement Therapy
  • Humans
  • Hypothyroidism / complications*
  • Hypothyroidism / diagnosis
  • Hypothyroidism / drug therapy
  • Hypothyroidism / physiopathology
  • Myxedema / diagnosis
  • Myxedema / drug therapy
  • Myxedema / etiology*
  • Myxedema / physiopathology
  • Severity of Illness Index
  • Thyroxine / therapeutic use
  • Treatment Outcome

Substances

  • Thyroxine