Acute Ulceronecrotic Gastritis With Cytomegalovirus Reactivation: Uncommon Toxicity of Immune Checkpoint Inhibitors in Microsatellite Instability-High Metastatic Colorectal Cancer

Clin Colorectal Cancer. 2020 Dec;19(4):e183-e188. doi: 10.1016/j.clcc.2020.04.006. Epub 2020 Jun 5.
No abstract available

Keywords: CMV reactivation; Colorectal cancer; Gastritis; Immunotherapy; Toxicity.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Colorectal Neoplasms / drug therapy*
  • Colorectal Neoplasms / genetics
  • Colorectal Neoplasms / immunology
  • Cytomegalovirus / immunology
  • Cytomegalovirus Infections / chemically induced
  • Cytomegalovirus Infections / diagnosis
  • Cytomegalovirus Infections / immunology*
  • Cytomegalovirus Infections / virology
  • Female
  • Gastric Mucosa / drug effects
  • Gastric Mucosa / immunology
  • Gastric Mucosa / pathology
  • Gastritis / chemically induced
  • Gastritis / diagnosis
  • Gastritis / immunology*
  • Gastritis / pathology
  • Humans
  • Immune Checkpoint Inhibitors / adverse effects*
  • Ipilimumab / adverse effects
  • Microsatellite Instability
  • Necrosis / chemically induced
  • Necrosis / diagnosis
  • Necrosis / immunology
  • Necrosis / pathology
  • Nivolumab / adverse effects
  • Stomach Ulcer / chemically induced
  • Stomach Ulcer / diagnosis
  • Stomach Ulcer / immunology*
  • Stomach Ulcer / pathology
  • Virus Activation / immunology

Substances

  • Immune Checkpoint Inhibitors
  • Ipilimumab
  • Nivolumab