Tracing a Path for Memory in the Hippocampus

Shayok Dutta; Sibo Gao; Joshua P Chu; Caleb Kemere

doi:10.1016/j.neuron.2020.06.034

Tracing a Path for Memory in the Hippocampus

Neuron. 2020 Jul 22;107(2):199-201. doi: 10.1016/j.neuron.2020.06.034.

Authors

Shayok Dutta¹, Sibo Gao¹, Joshua P Chu¹, Caleb Kemere²

Affiliations

¹ Department of Electrical and Computer Engineering, Rice University, Houston, TX, USA.
² Department of Electrical and Computer Engineering, Rice University, Houston, TX, USA; Neuroscience Program, Baylor College of Medicine, Houston, TX, USA. Electronic address: caleb.kemere@rice.edu.

Abstract

The hippocampal activity supporting trace fear conditioning has long been mysterious, but a leading hypothesis posits "time-cell"-like sequential patterns. In this issue of Neuron, Ahmed et al. (2020) present new data suggesting that, at least during the first session of learning, a subset of neurons coalesce to selectively encode the task but without expressing reliable sequences.

Publication types

Comment

MeSH terms

Fear
Hippocampus*
Learning
Memory*
Neurons

Grants and funding

R01 NS115233/NS/NINDS NIH HHS/United States