Transient Macular Thinning during the Use of Heavy Silicone Oil, Densiron 68

Curr Eye Res. 2021 Mar;46(3):350-354. doi: 10.1080/02713683.2020.1795885. Epub 2020 Jul 23.

Abstract

Background: To evaluate the effect of short-term Densiron tamponade on macular thickness.

Methods: Retrospective case series. Data were collected from charts of patients who received short-term (less than 90 days) Densiron tamponade. The OCT parameters were compared between Densiron in situ and after Densiron removal and to the fellow eye.

Results: Twenty eyes were included in the analysis. Although there was a trend toward thinner CRT with Densiron in situ in situ the operated eye when compared to the fellow eye (248 and 264 microns, respectively, p = .066), this difference disappeared after DR. At the final OCT there was a statistically significant recovery in the CRT (from 248 to 277 microns, P = .001) and no statistical difference between operated and the fellow eye (p = .265) with no evidence of ERM or CME.

Conclusions: We found transient macular thinning that resolved after Densiron removal with no evidence of long-term macular thinning in eyes treated with Densiron tamponade for retinal detachment.

Keywords: OCT; Retinal detachment; heavy silicone oil; macula.

Publication types

  • Observational Study

MeSH terms

  • Disease Progression
  • Endotamponade / methods*
  • Female
  • Humans
  • Macula Lutea / diagnostic imaging*
  • Male
  • Middle Aged
  • Retinal Detachment / diagnosis
  • Retinal Detachment / surgery*
  • Retrospective Studies
  • Silicone Oils / pharmacology*
  • Tomography, Optical Coherence / methods*
  • Vitrectomy / methods*

Substances

  • Silicone Oils
  • densiron-68