The effect of a split portion of flaxseed on 24-h blood glucose response

Eur J Nutr. 2021 Apr;60(3):1363-1373. doi: 10.1007/s00394-020-02333-x. Epub 2020 Jul 22.

Abstract

Purpose: Flaxseed can be effective at lowering and stabilising blood glucose responses. The aim of this study was to determine whether flaxseed could lower blood glucose response more effectively when consumed as a single portion of 30 g, or a split portion consumed three times per day (10 g flaxseed per portion).

Methods: The study was a randomised, repeated measures, cross-over design. Fifteen healthy participants consumed either (1) three flaxseed muffins containing a total of 30 g of flaxseed once in the morning, (2) three flaxseed muffins consumed at three different timepoints across the day (10 g flaxseed per muffin) or (3) three control muffins consumed at three different timepoints across the day (0 g flaxseed). The 24-h blood glucose response was measured using a continuous glucose monitor.

Results: The results of this study demonstrated that flaxseed muffins given three times a day were effective at lowering and maintaining blood glucose levels over 24 h, compared to the control muffins and that both flaxseed treatments resulting in a lower blood glucose iAUC during the night.

Conclusion: The results of this study indicated that adding flaxseed to a daily diet produced a lower glucose profile over 24 h in a free-living context compared to the control muffins.

Keywords: 24 blood glucose profile; Blood glucose; Blood glucose incremental area under the curve (iAUC); Continuous glucose monitor; Flaxseed; Linseed.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Blood Glucose
  • Cross-Over Studies
  • Diet
  • Flax*
  • Glucose
  • Humans

Substances

  • Blood Glucose
  • Glucose