Interleukin-22 in acute-on-chronic liver failure: A matter of ineffective levels, receptor dysregulation or defective signalling?

Affiliations

• ¹ Department of Internal Medicine I, University Hospital Frankfurt, Goethe University, Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany.
• ² Pharmazentrum Frankfurt/ZAFES, Goethe University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany.
• ³ European Foundation for the Study of Chronic Liver Failure, Barcelona, Spain; Hospital Clínic-IDIBAPS, Barcelona, Spain.
• ⁴ Department of Gastroenterology and Hepatology, University Hospital Essen, University of Duisburg-Essen, Hufelandstr. 55, 45147 Essen, Germany.
• ⁵ Department of Internal Medicine I, University Hospital Frankfurt, Goethe University, Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany; European Foundation for the Study of Chronic Liver Failure, Barcelona, Spain. Electronic address: jonel.trebicka@kgu.de.