Recent advances of two-dimensional materials in smart drug delivery nano-systems

Bioact Mater. 2020 Jul 15;5(4):1071-1086. doi: 10.1016/j.bioactmat.2020.06.012. eCollection 2020 Dec.

Abstract

Smart drug delivery nano-systems show significant changes in their physical or chemical properties in response to slight change in environmental physical and/or chemical signals, and further releasing drugs adjusted to the progression of the disease at the right target and rate intelligently. Two-dimensional materials possess dramatic status extend all over various scientific and technological disciplines by reason of their exceptional unique properties in application of smart drug delivery nano-systems. In this review, we summarized current progress to highlight various kinds of two-dimensional materials drug carriers which are widely explored in smart drug delivery systems as well as classification of stimuli responsive two-dimensional materials and the advantages and disadvantages of their applications. Consequently, we anticipate that this review might inspire the development of new two-dimensional materials with smart drug delivery systems, and deepen researchers' understanding of smart nano-carries based on two-dimensional materials.

Keywords: Disease; Nano-carriers; Smart drug delivery system; Two-dimensional materials.

Publication types

  • Review