Erythroblastic sarcoma presenting as a unilateral pleural effusion in a patient with myelodysplastic syndrome/myeloproliferative neoplasm-Case report with cytologic and histologic findings

Diagn Cytopathol. 2020 Dec;48(12):E18-E21. doi: 10.1002/dc.24540. Epub 2020 Jul 21.

Abstract

Erythroblastic sarcoma (ES) is an extremely rare extramedullary solid tumor of immature erythroid cells, with around a dozen human cases to our knowledge presented so far in the english literature, none of the cases presenting as pleural effusion. Here we describe a case of ES in a thoracic wall diagnosed by cytological examination of pleural effusion with histologic correlation in a 53-year-old patient with a 10-month history of myelodysplastic syndrome/myeloproliferative neoplasm with grade III reticulin myelofibrosis.

Keywords: cytopathology; erythroblastic sarcoma; myelodysplastic syndrome; myeloproliferative neoplasm; pleural effusion.

Publication types

  • Case Reports

MeSH terms

  • Erythroblasts / pathology*
  • Humans
  • Middle Aged
  • Myelodysplastic Syndromes / diagnosis*
  • Myelodysplastic Syndromes / pathology*
  • Pleural Effusion / diagnosis*
  • Pleural Effusion / pathology*
  • Pleural Neoplasms / diagnosis
  • Pleural Neoplasms / pathology
  • Primary Myelofibrosis / diagnosis
  • Primary Myelofibrosis / pathology
  • Sarcoma / diagnosis*
  • Sarcoma / pathology*
  • Thoracic Wall / pathology