Food biopharmaceuticals as part of a sustainable bioeconomy: Edible vaccines case study

Abstract

The lack of immunization in developing countries is undoubtedly the most serious consequence of the difficulty in accessing traditional vaccination systems. The World Health Organization (WHO) has aimed to find low-cost vaccines, which are accessible to the population and are easy to store and distribute without the need for refrigeration. There is literature support that orally administered edible vaccines are promising agents to reduce the incidence of diseases such as hepatitis and diarrhoea, especially in the developing world. This article focuses on the study of the suitability of edible vaccines as biopharmaceuticals in the context of the 2030 Agenda for Sustainable Development, allowing to comprehensively address both malnutrition and the degree of immunization, mainly in the child population in developing countries. This is embedded within the scope of a new concept promulgated by the UN and FAO called' Therapeutic Food' or 'Ready to Use Therapeutic Food'. Biopharmaceuticals such as edible processed vaccines have the potential to play an important role in increasing global health to achieve the 2030 - Sustainable Development Goals (SDGs), and beyond, as a solution to the dual problem of malnutrition and immunoprophylaxis as part of a sustainable bioeconomy. This article reviews their most promising applications, as well as the problems of a scientific and socioeconomic nature, including the complex current legislation that restricts their implementation.

Keywords: Edible vaccines; Food biopharmaceuticals; Inmunization; Therapeutic food.