3D printing for drug delivery and biomedical applications

Sarwar Beg; Waleed H Almalki; Arshi Malik; Mohd Farhan; Mohammad Aatif; Ziyaur Rahman; Nabil K Alruwaili; Majed Alrobaian; Mohammed Tarique; Mahfoozur Rahman

doi:10.1016/j.drudis.2020.07.007

3D printing for drug delivery and biomedical applications

Drug Discov Today. 2020 Sep;25(9):1668-1681. doi: 10.1016/j.drudis.2020.07.007. Epub 2020 Jul 17.

Authors

Affiliations

¹ Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India. Electronic address: sarwar.beg@gmail.com.
² Department of Pharmacology and Toxicology, College of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia.
³ Department of Clinical Biochemistry, College of Medicine, King Khalid University, Abha, Saudi Arabia.
⁴ Department of Biology, College of Basic Sciences, King Faisal University, Al Ahsa, Saudi Arabia.
⁵ Department of Public Health, College of Applied Medical Sciences, King Faisal University, Al Ahsa, Saudi Arabia.
⁶ Irma Lerma Rangel College of Pharmacy, Texas A&M Health Science Center, Texas A&M University, College Station, Texas, USA.
⁷ Department of Pharmaceutics, College of Pharmacy, Jouf University, Sakakah, Saudi Arabia.
⁸ Department of Pharmaceutics and Industrial Pharmacy, College of Pharmacy, Taif University, Taif, Saudi Arabia.
⁹ Center for Interdisciplinary Research in Basic Science (CIRBSc), Jamia Millia Islamia, New Delhi, India.
¹⁰ Department of Pharmaceutical Sciences, SIHAS, Faculty of Health Science, Sam Higginbottom University of Agriculture, Technology and Sciences, Allahabad, India. Electronic address: mahfoozkaifi@gmail.com.

PMID: 32687871
DOI: 10.1016/j.drudis.2020.07.007

Abstract

Pharmaceutical product development is continuously witnessing innovations for the design of new delivery systems to improve the therapeutic efficacy of drugs. 3D-printing technology has been used to design customized personalized medication to provide maximal therapeutic benefits for patients. I addition, 3D printing has also been used to manufacture drug delivery systems and biomedical devices to establish a paradigm shift in the healthcare industry. In this review, we provide an update on current progress, technological gaps, and regulatory considerations in 3D-printing technology.

Publication types

Review

MeSH terms

Biomedical Engineering
Drug Delivery Systems*
Humans
Legislation, Drug
Printing, Three-Dimensional*
Technology, Pharmaceutical