Evolution and Antigenic Drift of Influenza A (H7N9) Viruses, China, 2017-2019

Jiahao Zhang; Hejia Ye; Huanan Li; Kaixiong Ma; Weihong Qiu; Yiqun Chen; Ziwen Qiu; Bo Li; Weixin Jia; Zhaoping Liang; Ming Liao; Wenbao Qi

doi:10.3201/eid2608.200244

Evolution and Antigenic Drift of Influenza A (H7N9) Viruses, China, 2017-2019

Emerg Infect Dis. 2020 Aug;26(8):1906-1911. doi: 10.3201/eid2608.200244.

Authors

Jiahao Zhang, Hejia Ye, Huanan Li, Kaixiong Ma, Weihong Qiu, Yiqun Chen, Ziwen Qiu, Bo Li, Weixin Jia, Zhaoping Liang, Ming Liao, Wenbao Qi

Abstract

After a sharp decrease of influenza A(H7N9) virus in China in 2018, highly pathogenic H7N9 viruses re-emerged in 2019. These H7N9 variants exhibited a new predominant subclade and had been cocirculating at a low level in eastern and northeastern China. Several immune escape mutations and antigenic drift were observed in H7N9 variants.

Keywords: China; H7N9 viruses; HPAI; antigenic drift; evolution; high pathogenicity; highly pathogenic avian influenza; influenza; influenza virus; low pathogenicity; viruses.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
China / epidemiology
Hemagglutinin Glycoproteins, Influenza Virus / genetics
Influenza A Virus, H7N9 Subtype* / genetics
Influenza in Birds*
Influenza, Human* / epidemiology

Substances

Hemagglutinin Glycoproteins, Influenza Virus