Multicompartment Polymeric Nanocarriers for Biomedical Applications

Macromol Rapid Commun. 2020 Sep;41(18):e2000298. doi: 10.1002/marc.202000298. Epub 2020 Jul 19.

Abstract

Multicompartment polymeric nanocarriers which mimic the compartmentalized architecture of living cells have received considerable research attention in the biomedical field. The advancement of synthetic polymeric chemistry has allowed multicompartment polymeric nanocarriers to be tailored for biomedical applications such as drug delivery, encapsulated catalysis, and artificial cellular mimics. In this review, polymer-based multicompartment nanocarriers (multicompartment micelles, multicompartment polymersomes, and capsosomes) have been discussed. This review focuses on multicompartment systems applied to biomedical applications over the last ten years. The synthetic procedures and structural properties that impact the specific application are also highlighted.

Keywords: capsosomes; cell mimics; drug delivery; multicompartment micelles; multicompartment polymersomes.

Publication types

  • Review

MeSH terms

  • Artificial Cells*
  • Drug Carriers*
  • Drug Delivery Systems
  • Micelles
  • Polymers

Substances

  • Drug Carriers
  • Micelles
  • Polymers