Multiple metal(loid)s bioaccessibility from cooked seafood and health risk assessment

Environ Geochem Health. 2020 Nov;42(11):4037-4050. doi: 10.1007/s10653-020-00661-9. Epub 2020 Jul 19.

Abstract

Seafood has been generally considered to be the main diet exposure source of metal(loid)s. We evaluated health risk of mercury (Hg), arsenic (As), cadmium (Cd), lead (Pb), chromium (Cr), nickel (Ni), copper (Cu), and zinc (Zn) through consumption of cooked seafood based on bioaccessibility, which was obtained by physiologically based extraction test method. Results showed that cooking practices could decrease metal(loid)s concentration from seafood (by 6.0-45.7%). Metal(loid)s release from seafood in this study followed the descending order of Hg > Zn > Ni > Cd > Pb > As > Cu > Cr. On average, cooking lowered the bioaccessibility of As, Hg, Cd, Pb, Ni, Cr, Cu, and Zn by 15.2, 26.1, 30.9, 30.7, 25.7, 31.2, 17.6, and 22.4%, respectively. Health risk calculation results showed that Cr, Ni, and Zn in seafood species in this study were within the human health benefits range. Hg, Cd, Pb, and Cu exposure from cooked seafood was within the safe dose. However, we found that there is a potential of having cancer (especially bladder and lung cancer) for people exposure to iAs from seafood based on bioaccessible contents the first time.

Keywords: Bioaccessibility; Cooking; Crustacea; Fish; Health risk.

MeSH terms

  • Animals
  • Biological Availability
  • Carcinogens / analysis
  • Carcinogens / toxicity
  • China
  • Cooking*
  • Dietary Exposure / adverse effects
  • Dietary Exposure / analysis
  • Food Contamination / analysis*
  • Humans
  • Lung Neoplasms / chemically induced
  • Metals, Heavy / analysis*
  • Metals, Heavy / pharmacokinetics
  • Metals, Heavy / toxicity
  • Risk Assessment
  • Seafood / adverse effects*
  • Seafood / analysis*
  • Urinary Bladder Neoplasms / chemically induced
  • Water Pollutants, Chemical / analysis
  • Water Pollutants, Chemical / toxicity

Substances

  • Carcinogens
  • Metals, Heavy
  • Water Pollutants, Chemical