Correlations between corneal biomechanics and specular microscopy in patient with cataract

Rom J Ophthalmol. 2020 Apr-Jun;64(2):132-145.

Abstract

This study aimed to analyze the connection between corneal biomechanics (corneal hysteresis, CH) and endothelial cell density of cornea (mean endothelial cell density, MCD) in patients diagnosed with cataract. This retrospective, observational study was performed in the Ophthalmology Clinic of the University Emergency Hospital in Bucharest. Of 60 patients (120 eyes) with cataract, who were included in this study, we analyzed the CH values obtained using with the Ocular Response Analyzer (ORA) and the MCD values obtained using the specular microscopy. The study groups comprised both men and women with ages ranging from 45 to 63 years. Patients were divided into three study groups according to CH values. In each batch, the CH values obtained with the Ocular Response Analyzer (ORA) were correlated with age, gender and MCD, then the subgroups were compared. All the data gathered showed no correlation to be statistically significant regarding the biomechanical properties of the cornea and the corneal endothelial cell density in patients with cataract.

Keywords: Ocular Response Analyzer; corneal biomechanics; corneal endothelial cell density; corneal hysteresis; specular microscopy.

Publication types

  • Observational Study

MeSH terms

  • Cataract / physiopathology*
  • Cornea / pathology
  • Cornea / physiopathology*
  • Diagnostic Techniques, Ophthalmological*
  • Elasticity
  • Endothelium, Corneal / pathology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Retrospective Studies