Biowarfare, bioterrorism and biocrime: A historical overview on microbial harmful applications

Forensic Sci Int. 2020 Sep:314:110366. doi: 10.1016/j.forsciint.2020.110366. Epub 2020 Jun 20.

Abstract

Microbial Forensics is a field that continues to grow in interest and application among the forensic community. This review, divided into two sections, covers several topics associated with this new field. The first section presents a historic overview concerning the use of microorganisms (or its product, i.e. toxins) as harmful biological agents in the context of biological warfare (biowarfare), bioterrorism, and biocrime. Each case is illustrated with the examination of case reports that span from prehistory to the present day. The second part of the manuscript is devoted to the role of MF and highlights the necessity to prepare for the pressing threat of the harmful use of biological agents as weapons. Preventative actions, developments within the field to ensure a timely and effective response and are discussed herein.

Keywords: Biocrime; Bioterrorism; Biowarfare; Genetics; Microbial forensics.

Publication types

  • Historical Article
  • Review

MeSH terms

  • Bacterial Infections
  • Biological Warfare / history*
  • Bioterrorism / history*
  • Crime / history*
  • Forensic Sciences
  • HIV Infections
  • High-Throughput Screening Assays
  • History, 15th Century
  • History, 16th Century
  • History, 17th Century
  • History, 18th Century
  • History, 19th Century
  • History, 20th Century
  • History, 21st Century
  • History, Ancient
  • History, Medieval
  • Humans
  • Machine Learning
  • Microbiological Techniques
  • Toxins, Biological / adverse effects

Substances

  • Toxins, Biological