Control of the properties of speckle patterns produced by mutual interference of light waves is important for various applications of multimode optical fibers. It has been shown previously that a high signal-to-noise ratio in a multimode fiber can be achieved by preferential excitation of lower order spatial eigenmodes in optical fiber communication. Here we demonstrate that signal spatial coherence can be tailored by changing relative contributions of the lower and higher order multimode fiber eigenmodes for the research of speckle formation and spatial coherence. It is found that higher order spatial eigenmodes are more conducive to the final speckle formation. The minimum speckle contrast occurs in the lower order spatial eigenmodes dominated regime. This work paves the way for control and manipulation of the spatial coherence of light in a multimode fiber varying from partially coherent or totally incoherent light.