Freezing activity brief data from a new FUS mutant zebrafish line

Maria-Letizia Campanari; Annis-Rayan Bourefis; Valerie Buee-Scherrer; Edor Kabashi

doi:10.1016/j.dib.2020.105921

Freezing activity brief data from a new FUS mutant zebrafish line

Data Brief. 2020 Jun 24:31:105921. doi: 10.1016/j.dib.2020.105921. eCollection 2020 Aug.

Authors

Maria-Letizia Campanari^{1

2}, Annis-Rayan Bourefis^{1

2}, Valerie Buee-Scherrer³, Edor Kabashi^{1

2}

Affiliations

¹ Imagine Institute, Institut National de la Santé et de la Recherche Médicale (INSERM) Unité 1163, Paris Descartes Université, Paris 75015, France.
² Sorbonne Université, Université Pierre et Marie Curie (UPMC), Université de Paris 06, INSERM Unité 1127, Centre National de la Recherche Scientifique (CNRS) Unité Mixte de Recherche 7225, Institut du Cerveau et de la Moelle Épinière (ICM), Paris 75013, France.
³ Université de Lille, Inserm, CHU-Lille, Alzheimer & Tauopathies, Lille, France.

Abstract

The data presented in this paper are related to the research article "Functional characterization of a FUS mutant zebrafish line as a novel genetic model for ALS". In this model the lack of fus causes reduced lifespan as well as impaired motor abilities associated with a decrease of motor neurons axons lenght and an increase of neuromuscular junctions fragmentation. Data in this article describes the global locomotor activity data at 3, 4 and 5 days post fertilization in WT, fus heterozygous (fus^+/-) and fus homozygous (fus^-/-) zebrafish embryos as a response to visual light stimulation, with particular attention on the freezing respose.

Keywords: Behaviour; FUS KO model; Freezing response; Visual stimulation with the automatized viewpoint zebrabox system; Zebrafish (Danio Rerio).