Role of Energy Excretion in Human Body Weight Regulation

Trends Endocrinol Metab. 2020 Oct;31(10):705-708. doi: 10.1016/j.tem.2020.06.002. Epub 2020 Jul 13.

Abstract

Food intake and energy expenditure are the typical determinants of body weight. Yet, recent observations underscore that a third and often-neglected factor, fecal energy loss, can influence energy balance. Here, we explore how macronutrient excretion modulates human energy homeostasis and highlight its potential impact on the propensity to gain weight.

Keywords: Luxuskonsumption; constitutional thinness; fecal and urinary energy loss; obesity; overfeeding; spendthrift and thrifty phenotypes.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Body Constitution / physiology*
  • Energy Intake / physiology*
  • Energy Metabolism / physiology*
  • Humans
  • Intestinal Elimination / physiology*
  • Weight Gain / physiology*