A laser-diode-based white lighting module is fabricated via spectral component optimization, which can achieve both high luminous flux and high color rendering index (CRI). In this work, the laser module is constituted by blue laser diodes (LDs) which excite YAG:Ce-Al2O3 and red LDs that can compensate for the lack of red spectrum to improve the CRI of the light source. To fulfill the requirements of flexibility and compactness of light source, the blue and red LDs beams are combined by optical fiber coupling. A simulation framework is employed to optimize the dominant wavelength of red LDs and the power ratio of red to blue LDs. According to the results of the integrating sphere, high luminous flux of 1102 lm and high CRI of 77.8 are achieved simultaneously, which is consistent with the simulation results. The tunable correlated color temperature (CCT) varying from 4000 K to 2800 K and high angular color uniformity (ACU) can be obtained.