Association of Topical Minoxidil With Autosomal Recessive Woolly Hair/Hypotrichosis Caused by LIPH Pathogenic Variants

Tomoki Taki; Kana Tanahashi; Takuya Takeichi; Takenori Yoshikawa; Yuya Murase; Kazumitsu Sugiura; Masashi Akiyama

doi:10.1001/jamadermatol.2020.2195

Association of Topical Minoxidil With Autosomal Recessive Woolly Hair/Hypotrichosis Caused by LIPH Pathogenic Variants

JAMA Dermatol. 2020 Oct 1;156(10):1030-1032. doi: 10.1001/jamadermatol.2020.2195.

Authors

Tomoki Taki¹, Kana Tanahashi¹, Takuya Takeichi¹, Takenori Yoshikawa¹, Yuya Murase¹, Kazumitsu Sugiura², Masashi Akiyama¹

Affiliations

¹ Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.
² Department of Dermatology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.

Abstract

This nonrandomized clinical trial evaluates the association of topical minoxidil with hypotrichosis in patients with autosomal recessive woolly hair/hypotrichosis carrying LIPH pathogenic variants.

Publication types

Clinical Trial

MeSH terms

Administration, Topical
Adolescent
Child
Child, Preschool
Female
Hair / abnormalities*
Hair / drug effects
Hair Diseases / diagnosis
Hair Diseases / genetics
Hair Follicle / diagnostic imaging
Hair Follicle / drug effects
Hair Follicle / growth & development
Humans
Hypotrichosis / diagnosis
Hypotrichosis / drug therapy*
Hypotrichosis / genetics
Lipase / genetics
Male
Minoxidil / administration & dosage*
Mutation
Photography
Prospective Studies
Scalp
Solutions
Treatment Outcome
Young Adult

Substances

LIPH protein, human
Solutions
Minoxidil
Lipase

Supplementary concepts

Woolly Hair, Autosomal Recessive