Time to clearance of abdominal septic focus and mortality in patients with sepsis

Rev Bras Ter Intensiva. 2020 Jun;32(2):245-250. doi: 10.5935/0103-507x.20200029. Epub 2020 Jun 24.
[Article in English, Portuguese]

Abstract

Objective: To assess the relationship between time to focus clearance and hospital mortality in patients with sepsis and septic shock.

Methods: This was an observational, single-center study with a retrospective analysis of the time to clearance of abdominal septic focus. Patients were classified according to the time to focus clearance into an early (≤ 12 hours) or delayed (> 12 hours) group.

Results: A total of 135 patients were evaluated. There was no association between time to focus clearance and hospital mortality (≤ 12 hours versus > 12 hours): 52.3% versus 52.9%, with p = 0.137.

Conclusion: There was no difference in hospital mortality among patients with sepsis or septic shock who had an infectious focus evacuated before or after 12 hours after the diagnosis of sepsis.

Objetivo: Aferir a relação entre tempo para evacuação de foco e mortalidade hospitalar em portadores de sepse e choque séptico.

Métodos: Estudo observacional, unicêntrico, com análise retrospectiva do tempo para evacuação de foco séptico abdominal. Os pacientes foram classificados conforme o tempo para evacuação do foco em grupo precoce (≤ 12 horas) ou tardio (> 12 horas).

Resultados: Foram avaliados 135 pacientes. Não houve associação entre tempo para evacuação do foco e mortalidade hospitalar (≤ 12 horas versus > 12 horas): 52,3% versus 52,9%, com p = 0,137.

Conclusão: Não houve diferença na mortalidade hospitalar entre pacientes com sepse ou choque séptico que tiveram foco infeccioso evacuado antes ou após 12 horas do diagnóstico de sepse.

Publication types

  • Observational Study

MeSH terms

  • Aged
  • Female
  • Hospital Mortality*
  • Humans
  • Intraabdominal Infections / mortality*
  • Intraabdominal Infections / therapy
  • Male
  • Middle Aged
  • Retrospective Studies
  • Sepsis / mortality*
  • Sepsis / therapy
  • Shock, Septic / mortality*
  • Shock, Septic / therapy
  • Time Factors