Purpose: whilst renal scintigraphy (RS) can be associated with interobserver variability, it remains the standard method of evaluating split renal function.
Aim: to compare the efficacy of the novel technique of kidney function assessment and renal scintigraphy.
Method: for this prospective single-arm study we recruited patients who were recommended dynamic renal scintigraphy with 99mTc-DTPA (diethylenetriaminepentacetate). After scintigraphy, mathematical analysis of computed tomography (MACT) was done in all patients, by a single person (SK) blinded to RS results.
Results: the study included a total of 97 patients with mean age of 50.9 (range, 23-78) years. From this sample, 65 were females and 32 males. All patients underwent both RS and contrast-enhanced computed tomography for further MACT in 2016-2018. CT results were found to be similar to renal scintigraphy results with Pearson correlation coefficient of 0.945 (р < 0.001). Substantial similarities in renal plasma flow for both kidneys were also observed (0.815, р < 0.001).
Conclusion: MACT proved feasible, effective and safe in estimating renal function. Its results are closely correlated with RS findings and could be easily integrated into surgical practice.
Keywords: 3D-models; Filtration; GFR; MSCT; Renal scintigraphy; Split renal function assessment.
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