Infantile hepatic haemangioendothelioma resection in a newborn: A case report and literature review

J Int Med Res. 2020 Jul;48(7):300060520934325. doi: 10.1177/0300060520934325.

Abstract

Infantile hepatic haemangioendothelioma (IHH) is the most common benign hepatic tumour in infants. However, experience of managing IHH is lacking and treatments for symptomatic IHH are controversial. Here we report the case of a patient with IHH treated by liver resection. A liver mass was found in a newborn by prenatal ultrasonography. The patient presented with abdominal distention with a tangible mass. Further imaging diagnosis and biopsy were carried out and complete surgical resection of the mass was performed. Histological examination confirmed IHH. The patient recovered uneventfully after surgery, with no additional therapy after discharge and no recurrence during follow-up. We also summarise previously published resected cases of IHH and review the surgical outcomes. Surgical resection and liver transplantation appear to be effective treatments for symptomatic IHH.

Keywords: Infantile hepatic haemangioendothelioma; liver resection; newborn; prenatal ultrasound; transplantation; treatment.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Female
  • Hemangioendothelioma* / diagnostic imaging
  • Hemangioendothelioma* / surgery
  • Hepatectomy
  • Humans
  • Infant
  • Infant, Newborn
  • Liver Neoplasms* / diagnostic imaging
  • Liver Neoplasms* / surgery
  • Neoplasm Recurrence, Local
  • Pregnancy