Anxiety and depression and its correlates in patients with coronavirus disease 2019 in Wuhan

Int J Psychiatry Clin Pract. 2021 Jun;25(2):109-114. doi: 10.1080/13651501.2020.1791345. Epub 2020 Jul 14.

Abstract

Objectives: Coronavirus disease 2019 (COVID-19) first broke-out in Wuhan China in December 2019, and spread throughout the entire country within a short time. This cross-sectional study investigated the prevalence of depression and anxiety and associated risk factors were analysed in patients with COVID-19.

Methods: This single-center cross-sectional study focussed on measuring depression and anxiety using self-report scales. Linear regression was used to determine independent predictors for depression and anxiety.

Results: A total of 78 patients who were confirmed to have COVID-19 were enrolled in the study. Prevalence of depression and anxiety symptoms were diagnosed in 35.9% and 38.5% of the patients, respectively. Multivariate linear regression analysis found female gender was an independent predictor for higher depression severity index. Having family members who were diagnosed with COVID-19 and family members who died from COVID-19 were independently associated with higher depression severity index and anxiety score.

Conclusions: Patients with COVID-19 especially those who had family members diagnosed with COVID-19 or died from COVID-19 were more susceptible to depression and anxiety than were other patients. Effective strategies should be pursued to improve the mental health of this patient population.Key pointsPatients with COVID-19 showed a significantly high prevalence of depression and anxiety.Female patients were associated with higher risk of depression.Patients with family members diagnosed as COVID-19 or died from this disease were associated with higher risk of depression and anxiety.

Keywords: COVID-19; Depression; anxiety.

MeSH terms

  • Anxiety / epidemiology
  • Anxiety / etiology*
  • COVID-19 / psychology*
  • China / epidemiology
  • Cross-Sectional Studies
  • Depression / epidemiology
  • Depression / etiology*
  • Family
  • Female
  • Humans
  • Linear Models
  • Male
  • Middle Aged
  • Prevalence
  • Psychiatric Status Rating Scales
  • Risk Factors
  • Sex Factors