Visible-Light Photoredox-Catalyzed Amidation of Benzylic Alcohols

J Org Chem. 2020 Sep 18;85(18):11679-11687. doi: 10.1021/acs.joc.0c01320. Epub 2020 Jul 23.

Abstract

A new photocatalyzed route to amides from alcohols and amines mediated by visible light is presented. The reaction is carried out in ethyl acetate as a solvent. Ethyl acetate can be defined a green and bio-based solvent. The starting materials such as the energy source are easily available, stable, and inexpensive. The reaction has shown to be general and high yielding.

Publication types

  • Research Support, Non-U.S. Gov't