Gait characteristics in individuals with Parkinson's disease during 1-minute treadmill walking

Byungjoo Noh; Changhong Youm; Myeounggon Lee; Sang-Myung Cheon

doi:10.7717/peerj.9463

Gait characteristics in individuals with Parkinson's disease during 1-minute treadmill walking

PeerJ. 2020 Jun 29:8:e9463. doi: 10.7717/peerj.9463. eCollection 2020.

Authors

Byungjoo Noh¹, Changhong Youm^{1

2}, Myeounggon Lee², Sang-Myung Cheon³

Affiliations

¹ Department of Health Care and Science, College of Health Sciences, Dong-A University, Busan, Republic of Korea.
² Biomechanics Laboratory, College of Health Sciences, Dong-A University, Busan, Republic of Korea.
³ Department of Neurology, School of Medicine, Dong-A University, Busan, Republic of Korea.

Abstract

Background: No previous study has examined the age-dependent characteristics of gait in individuals between 50 and 79 years simultaneously in healthy individuals and individuals with Parkinson's disease (PD) over continuous gait cycles. This study aimed to investigate age-related differences in gait characteristics on individuals age ranged 50-79 years, including individuals with PD, during a 1-minute treadmill walking session. Additionally, we aimed to investigate the differences associated with spatiotemporal gait parameters and PD compared in age-matched individuals.

Methods: This study included 26 individuals with PD and 90 participants age ranged 50-79 years. The treadmill walking test at a self-preferred speed was performed for 1 min. The embedded inertial measurement unit sensor in the left and right outsoles-based system was used to collect gait characteristics based on tri-axial acceleration and tri-axial angular velocities.

Results: Participants aged >60 years had a decreased gait speed and shortened stride and step, which may demonstrate a distinct shift in aging (all p < 0.005). Individuals with PD showed more of a decrease in variables with a loss of consistency, including gait asymmetry (GA), phase coordination index (PCI) and coefficient of variation (CV) of all variables, than age-matched individuals (all p < 0.001). Gait speed, stride and step length, stance phase, variability, GA and PCI were the variables that highly depended on age and PD.

Discussion: Older adults could be considered those older than 60 years of age when gait alterations begin, such as a decreased gait speed as well as shortened stride and step length. On the other hand, a loss of consistency in spatiotemporal parameters and a higher GA and PCI could be used to identify individuals with PD. Thus, the CV of all spatiotemporal parameters, GA and PCI during walking could play an important role and be useful in identifying individuals with PD.

Conclusion: This study provided the notable aging pattern characteristics of gait in individuals >50 years, including individuals with PD. Increasing age after 60 years is associated with deterioration in spatiotemporal parameters of gait during continuous 1-minute treadmill walking. Additionally, GA, PCI and the CV of all variables could be used to identify PD which would be placed after 70 years of age. It may be useful to determine the decline of gait performance in general and among individuals with PD.

Keywords: Aging; Gait; Inertial measurement unit; Parkinson’s; Wearable sensor.

Grants and funding

This study was supported by the Dong-A University research fund. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.