Heart transplantation in the early phase of the COVID-19 pandemic: A single-center case series

Clin Transplant. 2020 Sep;34(9):e14042. doi: 10.1111/ctr.14042. Epub 2020 Aug 6.

Abstract

The infectious disease coronavirus disease 2019 (COVID-19) was declared a pandemic by the World Health Organization in March 2020. The impact of COVID-19 on solid organ transplantations, including heart transplantation, is currently unclear. Many transplant programs have been forced to swiftly re-evaluate and adapt their practices, leading to a marked decrease in transplants performed. This trend has been due to various factors, including increased donor COVID-19 screening scrutiny and recipient waiting list management in anticipation of COVID-19 critical care surge capacity planning. In the face of these unknown variables, determining when and how to proceed with transplantation in our population of patients with end-stage cardiomyopathies is challenging. Here, we describe our center's experience with orthotopic heart transplantation (OHT) in one of the country's pandemic epicenters, where we performed eight OHTs in the first 2 months after community spread began in late February 2020.

Keywords: COVID-19; SARS-CoV-2; coronavirus; heart transplantation; pandemic.

MeSH terms

  • Aged
  • COVID-19 / diagnosis
  • COVID-19 / epidemiology
  • COVID-19 / etiology
  • COVID-19 / prevention & control*
  • COVID-19 Testing
  • Female
  • Heart Failure / surgery*
  • Heart Transplantation*
  • Humans
  • Infection Control / methods
  • Los Angeles / epidemiology
  • Male
  • Middle Aged
  • Pandemics
  • Perioperative Care / methods
  • Postoperative Complications / diagnosis
  • Postoperative Complications / epidemiology
  • Postoperative Complications / prevention & control*
  • Treatment Outcome