Chronic suppurative otitis media due to Streptomyces cacaoi, the second case report in human infection

BMC Infect Dis. 2020 Jul 11;20(1):499. doi: 10.1186/s12879-020-05222-0.

Abstract

Background: Streptomyces cacaoi, Gram-positive, branched, filamentous bacillus forms without fragmentation, are saprophytic soil organisms rarely known to cause invasive infections other than mycetoma. Here we describe a case of chronic suppurative otitis media caused by Streptomyces cacaoi in a patient with hyperlipidemia in China.

Case presentation: A 62-year-old female patient with hyperlipidemia suffered chronic suppurative otitis media caused by Streptomyces cacaoi. She had a favorable outcome with a 4-week course of ofloxacin ear drops.

Conclusions: Streptomyces cacaoi is rarely reported to cause human infection. The introduction of molecular techniques improves the ability to identify rare species such as Streptomyces considerably. We report the case improve our ability to identify this pathogen and expand the range of known bacterial causes of human infection.

Keywords: Case report; Chronic suppurative otitis media; Streptomyces cacaoi.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / therapeutic use
  • China
  • Female
  • Gram-Positive Bacterial Infections / drug therapy*
  • Gram-Positive Bacterial Infections / microbiology*
  • Humans
  • Middle Aged
  • Ofloxacin / administration & dosage
  • Ofloxacin / therapeutic use
  • Otitis Media, Suppurative / drug therapy*
  • Otitis Media, Suppurative / microbiology*
  • Streptomyces / genetics
  • Streptomyces / isolation & purification
  • Streptomyces / pathogenicity*
  • Treatment Outcome
  • Tympanoplasty / methods

Substances

  • Anti-Bacterial Agents
  • Ofloxacin

Supplementary concepts

  • Streptomyces cacaoi