The long-term impact of peripheral cannulation for redo cardiac surgery

J Card Surg. 2020 Aug;35(8):1920-1926. doi: 10.1111/jocs.14852. Epub 2020 Jul 11.

Abstract

Background: Redo cardiac surgery carries an inherent risk for adverse short-term outcomes and worse long-term survival. Strategies to mitigate these risks have been numerous, including initiation of cardiopulmonary bypass via peripheral cannulation before resternotomy. This study evaluated the impact of central versus peripheral cannulation on long-term survival after redo cardiac surgery.

Methods: This was an observational study of open cardiac surgeries between 2010 and 2018. Patients undergoing open cardiac surgery that utilized cardiopulmonary bypass, who also had more than equal to 1 prior cardiac surgery, were identified. Kaplan-Meier survival estimation and multivariable Cox regression analysis were performed to assess the impact of peripheral cannulation on survival. To isolate long-term survival, patients with operative mortality were excluded and survival time was counted from the date of discharge until the date of death.

Results: Of the 1660 patients with more than equal to 1 prior cardiac surgery, 91 (5.5%) received peripheral cannulation. After excluding patients with operative mortality and after multivariable risk-adjustment, the peripheral cannulation group had significantly increased hazard of death, as compared to the central cannulation group (HR 1.53, 95% CI: 1.01, 2.30, P = .044). Yet, there were no relevant differences for other postoperative outcomes, including blood product requirement, prolonged ventilation (>24 hours), pneumonia, reoperation for bleeding, stroke, sepsis, and new dialysis requirement.

Conclusions: This is the first study reporting the long-term impact of peripheral cannulation for redo cardiac surgery after excluding patients with operative mortality. These data suggest that central cannulation may to be the preferred approach to redo cardiac surgery whenever safe and possible.

Keywords: aorta and great vessels; cardiac surgery; redo cardiac surgery.

Publication types

  • Observational Study

MeSH terms

  • Aged
  • Cardiac Surgical Procedures / adverse effects*
  • Cardiac Surgical Procedures / methods*
  • Cardiac Surgical Procedures / mortality*
  • Cardiopulmonary Bypass / adverse effects
  • Cardiopulmonary Bypass / methods
  • Catheterization, Central Venous / adverse effects*
  • Catheterization, Central Venous / mortality*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Reoperation / adverse effects*
  • Reoperation / mortality*
  • Risk
  • Safety
  • Survival Rate
  • Time Factors