Early diagnosis of chemotherapy-induced cardiotoxicity by cardiac MRI

Riccardo Cau; Pierpaolo Bassareo; Valeria Cherchi; Vitanio Palmisano; Jasjit S Suri; Michele Porcu; Antonella Balestrieri; Gianluca Pontone; Luca Saba

doi:10.1016/j.ejrad.2020.109158

Early diagnosis of chemotherapy-induced cardiotoxicity by cardiac MRI

Eur J Radiol. 2020 Sep:130:109158. doi: 10.1016/j.ejrad.2020.109158. Epub 2020 Jul 1.

Authors

Riccardo Cau¹, Pierpaolo Bassareo², Valeria Cherchi¹, Vitanio Palmisano³, Jasjit S Suri⁴, Michele Porcu¹, Antonella Balestrieri¹, Gianluca Pontone⁵, Luca Saba⁶

Affiliations

¹ Department of Radiology, Azienda Ospedaliero Universitaria (A.O.U.), di Cagliari - Polo di Monserrato, s.s. 554 Monserrato, Cagliari, 09045, Italy.
² University College of Dublin, Mater Misericordiae University Hospital and Our Lady's Children's Hospital, Crumlin, Dublin, Ireland.
³ Department of Radiology, Azienda Ospedaliero Universitaria (A.O.U.), di Cagliari - Polo di Monserrato, s.s. 554 Monserrato, Cagliari, 09045, Italy; Radiology Department, Miulli Hospital, Acquaviva delle Fonti, Italy Strada Prov. 127 Acquaviva - Santeramo Km. 4,100, 70021, Acquaviva delle Fonti, BA, Italy.
⁴ Diagnostic and Monitoring Division, AtheroPoint™ LLC, Roseville, CA, 95661, United States.
⁵ Centro Cardiologico Monzino, IRCCS, Milan, Italy.
⁶ Department of Radiology, Azienda Ospedaliero Universitaria (A.O.U.), di Cagliari - Polo di Monserrato, s.s. 554 Monserrato, Cagliari, 09045, Italy. Electronic address: lucasaba@tiscali.it.

PMID: 32652404
DOI: 10.1016/j.ejrad.2020.109158

Abstract

Survival rate in cancer patients has improved over the course of the years. In cancer survivors, cardiovascular disease is the second leading cause of mortality and early detection and serial monitoring of cardiotoxicity are key factors towards the improvement of patients' outcomes. This review article will provide an overview of the existing literature regarding the tools that MRI can offer in the early diagnosis of myocardial damage.

Keywords: Cardiac MRI; Cardiooncology; ECV; Myocardial strain; T1 mapping; T2 mapping.

Publication types

Review

MeSH terms

Antineoplastic Agents / adverse effects*
Cardiotoxicity / diagnostic imaging
Cardiotoxicity / etiology
Female
Heart / diagnostic imaging
Heart Diseases / chemically induced*
Heart Diseases / diagnostic imaging*
Humans
Magnetic Resonance Imaging / methods*

Substances

Antineoplastic Agents