SnapShot: Extracellular Vesicles

Federico Cocozza; Eleonora Grisard; Lorena Martin-Jaular; Mathilde Mathieu; Clotilde Théry

doi:10.1016/j.cell.2020.04.054

SnapShot: Extracellular Vesicles

Cell. 2020 Jul 9;182(1):262-262.e1. doi: 10.1016/j.cell.2020.04.054.

Authors

Federico Cocozza¹, Eleonora Grisard², Lorena Martin-Jaular², Mathilde Mathieu¹, Clotilde Théry²

Affiliations

¹ Institut Curie, INSERM U932, PSL Université, 26 rue d'Ulm, Paris 75005, France; Université de Paris, 85 Bd St germain, Paris 75006, France.
² Institut Curie, INSERM U932, PSL Université, 26 rue d'Ulm, Paris 75005, France.

PMID: 32649878
DOI: 10.1016/j.cell.2020.04.054

Abstract

Cells release a variety of extracellular vesicles (EVs; including exosomes, microvesicles, and many others) into their environment. EVs can bud in endosomes or directly at the plasma membrane, carrying a selection of components from the cell and displaying various functional properties. Different techniques can be used to separate EV subtypes and EVs from co-isolated components, resulting in preparations of different abundance and purity.

MeSH terms

Endosomes / metabolism
Extracellular Vesicles / metabolism*
Humans