Abstract
A 40-year-old woman presented with a productive cough and shortness of breath that limited her regular activities. Her past medical history was relevant for hypertension since 2016; it is well controlled and treated with enalapril 5 mg twice daily. She also revealed a past wood smoke exposure of 2 hours per day for 10 years during her childhood. A chest computed tomography (CT) scan was performed which showed a 30-mm lung nodule in the lower left lobe and mediastinal and ipsilateral pleural thickening with moderate pleural effusion and several bilateral lung metastases.
MeSH terms
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Acrylamides / therapeutic use*
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Adult
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Aniline Compounds / therapeutic use*
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Brain Neoplasms / diagnosis
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Brain Neoplasms / drug therapy
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Brain Neoplasms / genetics
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Brain Neoplasms / secondary
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Carcinoma, Non-Small-Cell Lung / diagnosis*
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Carcinoma, Non-Small-Cell Lung / drug therapy
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Carcinoma, Non-Small-Cell Lung / genetics
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Carcinoma, Non-Small-Cell Lung / pathology
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ErbB Receptors / genetics
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Female
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Humans
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Lung Neoplasms / diagnosis*
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Lung Neoplasms / drug therapy
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Lung Neoplasms / genetics
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Lung Neoplasms / pathology
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Mutation*
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Protein Kinase Inhibitors / therapeutic use
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Treatment Outcome
Substances
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Acrylamides
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Aniline Compounds
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Protein Kinase Inhibitors
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osimertinib
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EGFR protein, human
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ErbB Receptors