Megestrol is a medication used to manage and treat significant, inexplicable weight loss in HIV/AIDS patients and anorexia or cachexia syndrome. It is in the progestin class of drugs. This activity outlines the indications, action, and contraindications for megestrol as a valuable agent in managing significant, inexplicable weight loss in HIV/AIDS patients and anorexia or cachexia syndrome. In addition, this activity will highlight the mechanism of action, adverse event profile, and other key factors, including off-label uses, dosing, pharmacodynamics, pharmacokinetics, and monitoring, pertinent for members of the interprofessional team in the treatment of patients with significant, inexplicable weight loss in HIV/AIDS patients and anorexia or cachexia syndrome, and related conditions.
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