Circulating tumor cells: Ready for translation?

J Exp Med. 2020 Aug 3;217(8):e20200356. doi: 10.1084/jem.20200356.

Abstract

Circulating tumor cells are tumor-derived pioneers responsible for the metastatic spread of cancer. Here, we outline recent discoveries, challenges, and future trends for circulating tumor cell investigations, arguing that the time is coming for translation of this work into clinical practice.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Biomarkers, Tumor* / immunology
  • Biomarkers, Tumor* / metabolism
  • Humans
  • Neoplastic Cells, Circulating* / immunology
  • Neoplastic Cells, Circulating* / metabolism
  • Neoplastic Cells, Circulating* / pathology
  • Translational Research, Biomedical*

Substances

  • Biomarkers, Tumor