Monomorphic Epitheliotropic Intestinal T-cell Lymphoma Involving the Lung and Brain: A Rare Case Study

Intern Med. 2020 Oct 15;59(20):2559-2563. doi: 10.2169/internalmedicine.4710-20. Epub 2020 Jul 7.

Abstract

Monomorphic epitheliotropic intestinal T-cell lymphoma (MEITL) is a primary intestinal T-cell lymphoma and other organ involvement is very rare. A rare case of MEITL involving the lung and brain is herein reported. The patient developed panperitonitis with a small intestinal perforation, and emergency surgery was performed. The pathological findings from the surgical specimens demonstrated atypical lymphoid cells which were positive for CD3, CD8, and CD56. Moreover, the pathological findings of lung specimens taken by bronchoscopy were consistent with those of the small intestine. It is therefore important to include the possibility of MEITL in the differential diagnosis of cancer patients.

Keywords: brain; lactate dehydrogenase; lung; metastasis; monomorphic epitheliotropic intestinal T-cell lymphoma.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Brain Neoplasms / secondary*
  • Enteropathy-Associated T-Cell Lymphoma / diagnosis
  • Enteropathy-Associated T-Cell Lymphoma / pathology*
  • Humans
  • Intestinal Neoplasms / diagnosis
  • Intestinal Neoplasms / pathology*
  • Lung Neoplasms / secondary*
  • Male