Unrelenting facial segmental hemangiomas: A case series of late growth and recurrent ulcerations

Abstract

Late growth of infantile hemangiomas is an uncommon complication. We report three patients with segmental facial hemangiomas who experienced late growth and recurrent ulceration predominantly of the lower lip. These patients shared common clinical features including involvement of the S3 facial segment, oral and airway hemangiomas, and vascular anomalies associated with PHACE syndrome. This report highlights a clinical presentation at-risk for late growth and recurrent ulceration.

Keywords: PHACE syndrome; hemangioma; propranolol; segmental hemangioma; ulceration.