Targeting IL-22 and IL-22R protects against experimental osteoarthritis

Cell Mol Immunol. 2021 May;18(5):1329-1331. doi: 10.1038/s41423-020-0491-y. Epub 2020 Jul 7.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antibodies, Neutralizing / pharmacology
  • Chondrocytes / drug effects
  • Chondrocytes / metabolism
  • Chondrocytes / pathology
  • Humans
  • Interleukin-22
  • Interleukins / metabolism*
  • Mice
  • Osteoarthritis / metabolism*
  • Osteoarthritis / pathology
  • Receptors, Interleukin / metabolism*
  • Signal Transduction / drug effects

Substances

  • Antibodies, Neutralizing
  • Interleukins
  • Receptors, Interleukin
  • interleukin-22 receptor