3-D retina organoids: Building platforms for therapies of the future

Jessica N Mazerik; Steven Becker; Paul A Sieving

doi:10.1177/2155179018773758

3-D retina organoids: Building platforms for therapies of the future

Cell Med. 2018 Jun 8:10:2155179018773758. doi: 10.1177/2155179018773758. eCollection 2018.

Authors

Jessica N Mazerik¹, Steven Becker¹, Paul A Sieving¹

Affiliation

¹ National Eye Institute, National Institutes of Health, Bethesda, USA.

Abstract

Across scientific disciplines, 3-D organoid culture systems offer platforms to integrate basic research findings with clinical care. The National Eye Institute mounted a $1.1 million 3-D Retina Organoid Challenge. Organoids developed through the Challenge will be valuable resources for drug screening, disease modeling, and precision and regenerative medicine.

Keywords: Retina; drug screening; organoid; precision medicine; regenerative medicine; stem cells.