Guideline for Limb-Salvage Treatment of Osteosarcoma

Orthop Surg. 2020 Aug;12(4):1021-1029. doi: 10.1111/os.12702. Epub 2020 Jul 6.

Abstract

Osteosarcoma is the most common primary malignant bone tumor, occurring mainly in children and adolescents, and the limbs are the main affected sites. At present, limb-salvage treatment is considered as an effective basic standard treatment for osteosarcoma of the limb. China has a vast territory, but the development of technology is not balanced,which requires sufficient theoretical coverage, strong technical guidance and the application of limb-salvage treatment guidelines to the treatment of osteosarcoma. Therefore, to standardize and promote the development of limb-salvage surgery technology and improve the success rate of limb-salvage treatment, this guide systematically introduces limb-salvage techniques for the treatment of patients with limb osteosarcoma through definition of limb-salvage treatment, surgical methods, efficacy evaluation, postoperative treatment and prevention of complications, rehabilitation guidance, and follow-up advice.

Keywords: Limb-salvage therapy; Neoadjuvant chemotherapy; Osteosarcoma.

MeSH terms

  • Bone Neoplasms / therapy*
  • China
  • Combined Modality Therapy
  • Guidelines as Topic
  • Humans
  • Limb Salvage / methods*
  • Osteosarcoma / therapy*
  • Salvage Therapy / methods*