[Hematopoietic stem cell transplantation ocular complications: Guidelines from the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC)]

Abstract

Introduction: Allogeneic stem cell transplantation is currently the only curative therapy for hematological disorders. This treatment can lead to complications, of which ophtalmological involvement.

Methods: We reviewed the literature and established accessible and convenient recommendations for hematologists and ophthalmologists.

Results: Ophtalmological follow-up should be done in every patient having had an allogeneic transplantation, by the hematologist questioning and by the ophthalmologist physical exam. Complications due to graft-versus-host disease (GVHD) or not due to GVHD are cited, as well as therapeutic options.

Discussion: Screening and treatment of ophthalmologic complications in allogeneic stem cells transplantation recipients requires a close collaboration between hematologists and ophthalmologists. The management of these patients by caregivers trained in these questions is encouraged.

Keywords: Allogreffe de cellules souches hématopoïétiques; Eye; Graft-versus-host disease; Hematopoietic stem cell allogeneic transplantation; Oculaire; Ocular; Ophtalmologic; Ophtalmologique; Réaction du greffon contre l’hôte; Œil.